20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1719 | Bufalin | ATPase | |
Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potenti... | |||
T0712 | Suloctidil | ATPase , Platelet aggregation | |
Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders. It is hepatotoxic and fatalities have occurred. | |||
T6443 | Chloroprocaine hydrochloride | Chloroprocaine HCl | ATPase , Others |
Chloroprocaine hydrochloride (Chloroprocaine HCl) is a local anesthetic during surgical procedures. | |||
T0490 | Chlorpropamide | Diabinese | ATPase , ABC |
Chlorpropamide (Diabinese) is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. | |||
T6953 | Prilocaine | Citanest,Propitocaine,NSC 40027 | ATPase , Sodium Channel |
Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures. | |||
TJP2872 | Acevaltrate | Acevaltratum,Acetoxyvaltrate | ATPase , Others |
1. Acevaltrate (Acevaltratum) displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1-6 uM. | |||
T0796 | Prilocaine hydrochloride | Prilocaine HCl,Propitocaine hydrochloride,Xylonest | ATPase , Sodium Channel |
Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions. | |||
T5S0890 | Oleandrin | Neriostene,Folinerin,Foliandrin | Apoptosis , ATPase , Potassium Channel , Sodium Channel |
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, ... | |||
T0295 | Digitoxin | Digitoxoside,Unidigin,Digitoxinum | ATPase , Others |
Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM). | |||
T2176 | 2,3-Butanedione 2-Monoxime | Diacetyl monoxime,2,3-Butanedione-2-monoxime | Akt |
2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction. | |||
TN5073 | Strophanthidin | Strophanthidine | ATPase , Calcium Channel |
Strophanthidin (Strophanthidine) can induce calcium overload in vivo. | |||
T2621 | Rostafuroxin | PST 2238 | ATPase , RSV |
Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension. | |||
T2922 | Phlorizin | Floridzin,NSC 2833,Phloridzin | ATPase , SGLT |
Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) . | |||
T8183 | Deslanoside | Desacetyllanatoside C,Deacetyllanatoside C | ATPase , Drug Metabolite |
Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p... | |||
T2O2668 | Oleic acid | Elaidoic acid,9Z-Octadecenoic acid,Oleate,9-Octadecenoic Acid,Glycon Wo,9-cis-Octadecenoic acid | Apoptosis , ATPase , Others , Endogenous Metabolite |
Oleic acid (Glycon Wo) is a natural product, a common saturated fatty acid found in a variety of animal and vegetable fats and oils. Palmitic acid is a Na+/K+ ATPase activator. | |||
T2822 | Ginsenoside Rb1 | Gypenoside Ⅲ,Gypenoside III | ATPase , Mitophagy , IRAK , NF-κB , Autophagy , HSV |
Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors. | |||
T27303 | Farglitazar | GI-262570,GI 262570,GI262570 | |
Farglitazar is a PPAR-γ agonist. GI262570 stimulates the ENaC and Na,K-ATPase system resulting in the increasing of water and sodium reabsorption in distal nephron. | |||
T3432 | Cinobufagin | Cinobufagine | Apoptosis , ATPase , Autophagy |
Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain. | |||
T36390 | Sodium oleate | Oleic acid sodium salt,Sodium oleate,cis-9-Octadecenoic acid sodium salt | ATPase |
Sodium oleate (cis-9-Octadecenoic acid sodium salt) (Oleic acid sodium) is an abundant monounsaturated fatty acid sodium. Sodium oleate is a Na+/K+ ATPase activator. | |||
T14052 | 5-IAF | 5-Iodoacetamidofluorescein | |
5-IAF is a fluorescein derivative of indoleacetamide, a fluorescent probe that can be used to label proteins and others containing free thiols (cysteine side chains). 5-IAF can label the catalytic (alpha) subunit of dog ... |